Undergraduate Research Winners
First Place
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UR-1195 Using Machine Learning to Diagnose Alzheimer's (Undergraduate Research) by , Abstract: Early detection of Alzheimer’s disease (AD) remains a significant clinical challenge, as the changes associated with cognitive decline are often subtle and difficult to identify through visual assessment alone. This study investigates modern machine learning methodologies to improve the prediction of cognitive impairment using volumetric MRI–derived region-of-interest (ROI) features. We constructed three binary classifiers [NC vs. AD, MCI vs. AD, and NC vs. MCI] and evaluated various algorithms, including logistic regression, random forests, neural networks, and support vector machines (SVMs). Using measurements generated from eight anatomical brain templates, our models learned patterns indicative of normal cognition, mild cognitive impairment, and Alzheimer’s disease. Among all tested approaches, the radial basis function (RBF) SVM consistently achieved the highest performance, reaching accuracies of approximately 70–80% depending on the classification task. We discuss the implications of this model’s dominance for future clinical applications and the continued development of machine learning–driven diagnostic tools. Department: Computer Science Supervisor: Prof. Sharon Perry Project Sponsor: Dr. Chen Zhao | |
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Second Place
UR-1167 OwlExchange (Undergraduate Research) by , , , , Abstract: OwlExchange is a secure, role-based campus marketplace designed to help Âé¶ą´«Ă˝
State University students buy, sell, exchange, and donate items in a trusted digital
environment. The platform replaces unorganized and unsafe exchanges occurring across
group chats and social media by providing a centralized system with authenticated
user accounts, item listings, and transparent communication. Built with a Flask (Python)
MVC architecture, Auth0 for secure identity management, and MySQL for persistent storage,
OwlExchange supports modular dashboards for buyers, sellers, and administrators, enabling
item management, interest requests, and platform oversight. By promoting reuse and
donation of textbooks, furniture, electronics, and other student items, the system
contributes to affordability and sustainability on campus. The project demonstrates
full-stack development, secure authentication design, UI/UX branding aligned with
KSU identity, and cloud deployment with a documented roadmap for future enhancements. Department: Information Technology Supervisor: Prof. Donald Privitera Sponsor: Assurant Global Technology | |
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Third Place
UR-0199 Blood Flow Simulation From Coronary Computed Tomography Angiography Using
Vnet (Undergraduate Research) by Abstract: Coronary artery disease (CAD) is one of the leading causes of death worldwide, making the assessment of blood flow and pressure distribution within coronary vessels essential for diagnosis and treatment planning. Fractional Flow Reserve (FFR) is a key measure used to determine the severity of arterial blockages, but traditional methods, such as invasive measurements or computational fluid dynamics (CFD) simulations, are not only time-consuming and costly but also invasive. This project explores the use of deep learning to predict blood pressure distribution in coronary arteries using a 3D convolutional neural network. The dataset consists of Coronary Computed Tomography Angiography (CCTA) scans paired with blood pressure obtained from CFD simulations. After preprocessing and voxelizing the CCTA scans, the VNet model learns to map the vessel’s geometry to its internal pressure distribution. Our model achieved a Pearson correlation of 0.93 and an R² score of 0.84 between the predicted and simulated pressures. These results indicate that VNet delivers accurate, spatially consistent pressure predictions that closely match CFD outputs while substantially reducing computation time. This approach underscores the potential of deep learning to accelerate non-invasive FFR estimation and enhance patient-specific cardiovascular analysis. Department: Computer Science Supervisor: Dr. Chen Zhao
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